Pretty cool; it has a Quake II Sonic Mayhem-ish feel that I like, and I dig the police sirens in the background, but I still prefer the simpler, original 3D Realms chiptune.
As far as the Duke is concerned, my favorite tune is probably Stabbing Westward's "I Won't Become the Thing I Hate" used in the Playstation Duke Nukem: Time to Kill game.