Well Trey, I dont know from experience but most of the later color games make distinctions on the box on compatibility. For example, my Asian hardcase cotton has a black and white logo saying "compatible with NGP" while Faselei says "Works exclusively with NeoGeo Pocket Color." That would lead me to believe that the answer to your question would be no, but I havent actually tried games like Faselei in a black and white unit.
John