I have used the SC 200 successfully with an MV-1 and many jamma boards.........
I guess if you were to use it with speakers rather than a at circuit, it might not be powerfull enough.
THe only boards that should have a problem with the SC 200 are ones that require a -5v to power an audio amp (Killer Instinct, CPS II, Mortal Combat) and boards that have some type of optical drive.